Does HRT decrease bone density?
There is some concern that hormone replacement therapy (HRT) may decrease bone density and increase the risk of fractures, especially in postmenopausal women. However, a number of studies have failed to find a significant association between HRT and bone density or fracture risk. In fact, some studies suggest that HRT may actually help protect against bone loss. For example, a study published in the journal Menopause found that women who took estrogen plus progestin had significantly greater bone mineral density at the hip than those who took placebo. Another study published in JAMA showed that estrogen alone was associated with significantly less hip fracture than placebo among postmenopausal women with osteopenia. It's important to note that not all forms of HRT are equal when it comes to preserving bone health; for example, transdermal estrogens (such as patches and gels) appear to be more beneficial than oral estrogens. So while there is still some uncertainty about the effects of HRT on bones, current evidence suggests that it does not pose a major threat to Bone Mineral Density (BMD).
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